Block of cardiac delayed-rectifier and inward-rectifier K+ currents by nisoldipine
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چکیده
منابع مشابه
Inward rectifier currents in pericytes.
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Hypercholesterolemia is an independent risk factor for development of cardiovascular disease1 and has been demonstrated to impair endothelium-dependent and independent vasodilatation.2 However, the mechanisms responsible for changes in vascular reactivity and impaired blood flow regulation induced by hypercholesterolemia remain unclear. Previous studies in cultured endothelial cells have shown ...
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BACKGROUND The effects of type 1 angiotensin II receptor antagonist losartan and its metabolite E3174 on transmembrane action potentials, hKv1.5, HERG, and I(Ks) currents were analyzed. METHODS AND RESULTS Guinea pig ventricular action potentials were recorded with microelectrode techniques and hKv1.5 and HERG currents with the whole-cell patch-clamp technique. I(Ks) was recorded in guinea pi...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 2003
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0705518